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George Clooney has issued a damning call for Joe Biden to quit the US presidential race, hours after senior Democrat Nancy Pelosi swerved questions about whether he should continue, BBC News reports.

The Hollywood actor and prominent Democratic fundraiser said that the president had won many battles in his career, "but the one battle he cannot win is the fight against time".

His comments came after Mrs Pelosi, the former House Speaker, joined growing disquiet in the party, saying that time was "running short" for Mr Biden, 81, to decide whether to stay in the race after his stumbling debate against Donald Trump.

The president has stated, repeatedly, that he is determined to remain as the Democratic party's candidate and beat Trump, 78, in November.

Clooney wrote in the New York Times that it was "devastating to say it", but the Joe Biden he met at a fundraising event three weeks ago was not the Biden of 2010. "He wasn’t even the Joe Biden of 2020," added the actor.

"He was the same man we all witnessed at the debate," Clooney said.

The fundraising event, co-hosted by Clooney in Los Angeles and also featuring Julia Roberts and Barbra Streisand, brought in a single-night record of roughly $30m (£23m) for the Biden campaign.

The Biden camp has hit back at the Hollywood star, with an unnamed source telling US media: “The President stayed for over 3 hours [at the fundraiser], while Clooney took a photo quickly and left.”

The president's campaign also pointed out that when he attended the fundraiser he had just arrived in Los Angeles from Italy, where he had been at the G7 summit.

In his op-ed, Clooney said: "Our party leaders need to stop telling us that 51 million people didn’t see what we just saw."

"This is about age. Nothing more," he continued. "We are not going to win in November with this president."

Clooney added that his concerns matched those of "every" member of Congress with whom he had spoken.

Asked to respond, Mr Biden's campaign referred to a letter the president sent Democrats in Congress that said he was "firmly committed" to his candidacy and beating Trump.

Yet public dissent continues to grow within Mr Biden's party as he faces scrutiny while hosting the Nato summit in Washington.