Society 11:54 26/07/2013

Scientists discover death can be SEEN spreading like a blue glowing wave through the body of a worm

British scientists have captured death spreading like a wave through the body of a worm, by studying the blue fluorescence that travels cell-to-cell until the whole organism is dead, the Daily Mail reported. 

Researchers from the Wellcome Trust and the Biotechnology and Biological Sciences Research Council (BBSRC) likened the spread of the blue glow travelling through the worm's body to that of the Grim Reaper, stalking death.

They believe that the research could eventually prove to be a useful model to understanding death in people and perhaps even lead to an increase in life expectancy.

When individual cells die, they trigger a chemical chain reaction that leads to the breakdown of cell components and a build-up of molecular debris.

The molecular mechanisms of this are reasonably well understood at a cellular level but we know much less about how death spreads throughout an organism at the end of its life.

In worms, the spread of death can be seen easily under a microscope as a wave of blue fluorescence travelling through the gut of the worm.

The study, published in PLoS Biology, reveals that this fluorescence is caused by a cell death pathway called necrosis and its spread throughout the organism is dependent on calcium signalling.

Professor David Gems from the Institute of Health Ageing at University College London, who led the study, said: 'We’ve identified a chemical pathway of self-destruction that propagate cell death in worms, which we see as this glowing blue fluorescence travelling through the body.

'It’s like a blue Grim Reaper, tracking death as it spreads throughout the organism until all life is extinguished.

'We found that when we blocked this pathway, we could delay death induced by a stress such as infection, but we couldn’t slow death from old age.

'This suggests that ageing causes death by a number of processes acting in parallel.'

The mechanisms involved are similar to those that are active in mammals, confirming that the worm can provide a useful model to understand cell death in people.

The source of the blue fluorescence was previously thought to be a substance called lipofuscin, which emits light of a similar colour and has been linked to ageing because it accumulates with increasing molecular damage.

However, scientists now think another molecule called anthranilic acid is the source of the blue hue and the study shows that lipofuscin is not involved.

Professor Gems said: 'Together the findings cast doubt on the theory that ageing is simply a consequence of an accumulation of molecular damage.

'We need to focus on the biological events that occur during ageing and death to properly understand how we might be able to interrupt these processes.'

 

 



Source Panorama.am
Share |
Տեքստում սխալ կամ վրիպակ նկատելու դեպքում, ուղարկեք խմբագրին հաղորդագրություն` նշելով տվյալ սխալը, այնուհետև սեղմելով Ctrl-Enter:

Newsfeed

14:08
German and Abkhaz observers positively asses the course of voting at Artsakh Constitutional referendum
Deputy Speaker of the Parliament of the unrecognized Abkhaz Republic Gamisonia Alekseyevna who is monitoring the Artsakh...
13:23
World oil prices rising
As a result of e-commerce in London and New York stock exchanges, the oil prices are rising, Gazeta.ru reports. According to the source, the...
13:16
Iranian government approves the joint use of Meghri-Norduz border gates
The Government of the Islamic Republic of Iran has endorsed the agreement on the joint use of Meghri-Norduz border gates, Iranian IRIB Agency...
12:48
President Bako Sahakyan congratulates on Artsakh Revival Day
The President of the Nagorno Karabakh Republic Bako Sahakyan has issued a congratulatory Address on the Artsakh Revival Day. As the Information...
12:15
Iran stage military drills in defiance of US sanctions
The Islamic Revolution Guards Corps (IRGC) Ground Force started the first phase of a large-scale military exercise in Dasht-e Kavir in central...
11:48
Constitutional Referendum voting kicks off in Artsakh
The Artsakh people are voting in a referendum on constitutional amendments which envisage a switch to a presidential form of governance. As the...
11:03
NKR Defense Army: Azerbaijani forces made 55 ceasefire violations overnight
The Azerbaijani forces violated the ceasefire along the Line of Contact between the Nagorno Karabakh Republic (NKR) and Azerbaijani opposing...
10:59
Vahan Martirosyan: Clayderman is always welcome in Armenia
Renown French pianist, composer and performer of classic and ethnic music Richard Clayderman will perform a concert at Karen Demirchyan Sports...
10:32
Berd-Tchambarak road opened
Armenia's Ministry of Transport, Communication and Information Technologies told Panorama.am that as of 19:00 February 20 no precipitation...
10:26
Armenian U-16 beats Andorra
The UEFA Development tournament match day 2 match between U-16 teams of Armenia and Andorra took place on Sunday. The match ended in draw 1-1,...
20:12
Police robot makes China debut
China’s first police robot completed its first official patrol of a railway station in the central Chinese province Henan earlier this...
19:49
Ferdowsi Cup: Rounds 7 and 8 over
Ferdowsi Cup chess championship underway in Tehran comes to its end. 8 out of 11 rounds have already been played. In Round 7, two Armenian GMs...
19:32
One dead, 20 injured as Brussels-bound train tips over in derailment
A train in Leuven, Belgium, has derailed leaving at least one person dead and 20 injured in the accident wreckage, the Express reports. As...
19:21
Road condition update: Several highways closed, difficult to pass in Armenia
The Ministry of Emergency Situations of Armenia reports that as of 18:00 February 18, several highways are closed or difficult to pass across...
18:57
Tablet production doubles in Armenia
According to the data released by Armenia’s National Statistical Service (NSS), in 2016 2012 units of tables were produced in Armenia. The...
18:35
Facilitation of Armenia-EU visa regime discussed within Munich Security Conference
Armenia’s Minister of Foreign Affairs Edward Nalbandian, who is taking part in Munich Security Conference, today met with EU Commissioner...
18:07
GM Aronian to compete with Evgeny Tomashevsky in Sharjah Grand Prix 2017
The opening ceremony and the drawing of lots of FIDE World Chess Sharjah Grand Prix took place. According to the drawing results, Armenian GM...
17:12
German journalist detained in Turkey
German correspondent for the daily "Die Welt" newspaper Deniz Yücel  has been taken into custody in Turkey. As Deutsche...
16:52
Iranian media’s assessments on Ilham Aliyev's promise and real steps
“Six months have passed since the agreement reached between Iranian and Azerbaijani presidents, however Azerbaijan has failed to set...
16:10
Armenia’s FM, OSCE Secretary General hold a meeting
Armenian Minister of Foreign Affairs Edward Nalbandian, who is on a working visit to Munich, held a meeting with Secretary General of the...
16:06
Former Foreign Minister Vartan Oskanian’s son arrested, suspected in kidnapping
Son of the Former Foreign Minister Vartan Oskanian was arrested on February 17 and suspected in participating a group kidnapping of a person and...
15:43
Serviceman killed in Nagorno Karabakh
On 18 February, at around 11:45, NKR Defense Army soldier Lernik Alexander Osyan (b. 1998) received a fatal gunshot wound in unknown...
15:28
Armenia’s Berd-Tchambarak highway closed
Armenia’s Ministry of Transport, Communication and Information Technologies told Panorama.am that as of 14:30 February 18, Vardenyats Pass...
15:04
Armenia delivers another batch of humanitarian aid to Syria
Armenia has delivered another humanitarian aid to the population of the worn-torn Syria according to the agreement reached between the defense...
14:33
President Sargsyan: Keep the powder dry, our struggle continues
“Some people in Azerbaijan keep harboring hopes that Armenia will be vulnerable while being engaged with elections. The adversary may try...
13:13
Earthquake recorded in Armenia’s Gegharkunik province
An earthquake of 2.8 magnitude was registered in Vahan village of Gegharkunik region of Armenia on Saturday at about 10:15 (GMT 06:15),...
13:07
The dream of an impoverished family living with 9 children in a damp and poor housing conditions
35-year-old Hasmik Sahakyan who lives in Geghahovit village of Gegharkunik province in Armenia has recently given birth to her ninth child....
11:58
Armenia’s FM discussed recent development in the Syrian conflict settlement with Staffan de Mistura
Armenian Foreign Minister Edward Nalbandian has met on Friday with the UN Secretary-General's Special Envoy for Syria Staffan de Mistura. As...
11:01
Ministry of Transport reports the situation on roads throughout Armenia
Armenia’s Ministry of Transport, Communication and Information Technologies told Panorama.am that as of 09:30, February 18 clear ice is...
10:39
Around 600 shots fired toward the Armenian positions
The Azerbaijani forces violated the ceasefire across the Line of Contact between the Nagorno Karabakh Republic (NKR) and Azerbaijani opposing...

Follow us and get updates!

Most popular articles

{"core.blocks.header.spell_message1":"Selected mistake: ","core.blocks.header.spell_message2":"Send a message about the mistake?"}