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Four people are dead after a prop plane crashed into a building this morning at an airport in Wichita, Kansas, ABC News reported, citing officials.

Five others have been rushed to a local hospital, fire marshal Brad Crisp said more than three hours after the crash.

"We don't know what may have caused the incident," Wichita Fire Department Chief Ron Blackwell said, noting that responders faced a "horrific firefight for several minutes."

The plane struck the top of the Flight Safety Building shortly before 10 a.m. and approximately 100 people were inside at the time, according to airport officials. The fatalities and injured were taken out of the building and the remaining individuals have all been accounted for.

Federal officials have confirmed that the incident is not related to terrorism.

The plane involved in the crash was a twin-engine Beechcraft that was taking off but lost power in one engine, according to the Federal Aviation Administration.

Keith Rose, the CEO of Rose Aircraft Services Inc., which owned the plane, confirmed that the pilot was one of the two fatalities. He was the only person on board. The three other fatalities were all individuals in the building, which housed Cessna Citation Jet Simulators.

Rose said that the plane was headed to Mena, Arkansas, "for painting and interior refurbishing work."